Rat Anti-Mouse CD107a/LAMP-1-FITC MBS673718 from MyBioSource.com

Product Specs
ItemRat Anti-Mouse CD107a/LAMP-1-FITC
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS673718
ApplicationsWB, FCM, IHC-fr, IP
ClonalityMonoclonal
ReactivityMouse (Ms)
ImmunogenMurine CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa)
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles.^1 It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion.^2 CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice.^3 LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.^4
Antibody TypeSecondary
HostRat
Clone1D4B
IsotypeIgG2a
TargetCD107a (LAMP-1)
FormatFluorescein (FITC) Conjugate
Conjugate/TagFITC
Quantity0.5 mg